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Graduate Research Associate

Posted on: 2012-09-07

EDUCATION

Rockefeller University, New York, NY / Cornell University, Ithaca, NY                                2006-2012

Ph.D, Chemical Biology Fellow ($180K award), GPA: 4.2/4.3

Peking University, Beijing, China                                                       2002-2006  

B.S. Chemistry. GPA: 3.85/4.00, ranked 7th out of 180, Chun-Tsung Scholarship ($5K, 1 out of 180)

TECHNICAL SKILLS

  • Five-year experience with molecular biology including cloning, PCR, RT-PCR, DNA mutagenesis and nucleic acid gel electrophoresis; Two-year experience with recombinant protein expression and purification (affinity chromatography, size exclusion chromatography and ion exchange chromatography)
  • Five-year experience with cell culture and spectroscopic techniques for protein analysis (hands-on experience with UV-vis, circular dichroism and fluorescence spectroscopy).
  • Eight-year experience with Microsoft Office software package (Word, Excel and Powerpoint).

PUBLICATIONS

  
  • ·Tan L, Kapoor TM. Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division. PNAS 2011 108(40):16(phone hidden)0.
  • Tseng BS, Tan L, Kapoor TM, Funabiki H. Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Dev Cell. 2010 18(6):903-12.
  • Li C, Qi Y, Teng X, Yang Z, Wei P, Zhang C, Tan L, et al. Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase. J Biol Chem. 2010 285(36):28134-40.
  • Chen H, Wei P, Huang C, Tan L, Liu Y, Lai L. Only one protomer is active in the dimer of SARS 3C-like proteinase. J. Biol Chem. 2006 281(20):13894-8.
  • Wei P, Fan K, Chen H, Ma L, Huang C, Tan L, et al. The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase. Biochem Biophys Res Commun. 2006 339(3):865-72.

ACADEMIC EXPERIENCE

Graduate Research Fellow, Rockefeller University, New York, NY                      2007-2012

Laboratory of Chemistry and Cell Biology (Mentor: Prof. Tarun M. Kapoor)

  • Created an automatic data analysis protocol that reduced analysis time by 60%
  • Published 2 peer-reviewed research papers (cited 12 times in a year) and co-authored 2 grant applications that resulted in $800K funding from National Institutes of Health
  • Mentored 5 PhD students, managed their projects, monitored progresses and provided feedback
  • Manage the lab mammalian cell tissue culture equipment usage

Undergraduate Research Fellow, Peking University, Beijing, China                     2003-2006

State Key Laboratory for Structural Chemistry of Unstable and Stable Species (Mentor: Prof. Luhua Lai)

  • Designed an assay for screening anti-viral drugs, reduced the cost of screening by 80%
  • Co-authored 3 peer-reviewed research papers that have been cited 48 times
  • Managed summer research project for an undergraduate student from Taiwan

PERSONAL

  • Languages: English (fluent), Mandarin (native), Shanghainese (native)
  • Volunteer: Participated in training program for disabled runners in Achilles Track Club; Facilitated socialization for psychiatric patients in the inpatient facility at NY Presbyterian Hospital