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Irina
US-Kentucky-Louisville
10+ yrs
Yes
Yes
Research Associate
To pursue a career within the Biotech/Pharmaceutical Industry
Irina Kirpich, PhD
OBJECTIVE To pursue a career within the Biotech/Pharmaceutical Industry
SUMMARY OF QUALIFICATIONS
A highly experienced and motivated Scientific Research Professionals, Ph.D. with more than 10 years of experience in clinical and experimental research; extensive background in Molecular and Cell Biology, Biochemistry, Immunology; strong record of publications; outstanding skills in recent molecular/cell biology techniques; excellent experimental design and data analysis skills; expertise in molecular mechanisms of metabolic diseases including obesity, insulin resistance, and liver disease, liver-gut interactions; nutrition.
PROFESSIONAL SKILLS
• Excellent experience in managing, planning, and executing research projects and clinical trials
• Strong knowledge in laboratory management, laboratory husbandry and cell culture techniques
• Hands-on experience in recent molecular biology techniques including RNA and DNA purification, gene expression analysis (microarray processing, PCR and qRT PCR), SDS-PAGE & Western Blot analysis
• Expertise in immune monitoring assays such as ELISA, Luminex
• Familiar with in vivo drug metabolism studies and pharmacokinetics
• Deep knowledge in statistical analysis. Great level of computer literacy and advanced knowledge of Microsoft applications, including Word, Excel, Access and PowerPoint
• Ability to critically analyze as well as possess a creative ability to bring "newness" to the work assignment
• Proven ability to report clinical and experimental research results in peer-reviewed, scientific journals; to present study at the scientific meetings
• Excellent organizational, interpersonal, written and oral communicational skills
• Excellent ability to communicate clearly, logically and persuasively on complex scientific topics for a diverse scientific and nonscientific audience
• Strong ability to work as part of a team as well as independently
PROFESSIONAL EXPERIENCE
2006– present, Research Associate
University of Louisville, Louisville, KY, USA
- Generate, analyze and summarize data for peer reviewed publications and meeting presentations in the project studying the molecular mechanisms of metabolic diseases including obesity, insulin resistance, and liver disease
- Oversee and troubleshoot laboratory techniques involving in the study of epigenetic mechanisms of gene regulation such as genome-wide DNA methylation microarray, histone modification assays
- Responsible for cDNA microarray gene expression data analysis and interpretation
Accomplishments:
- Excellence in Research Award, American Association of Clinical Chemistry, 2009
- Invited talk at the Experimental Biology Annual Meeting, San Diego, 2008
- Distinguish Abstract Award, American National Academy of Clinical Biochemistry, 2006
2001-2006, Associate Professor
Department of Biochemistry, Medical School, Northern State University, Arkhangelsk, Russia
- Led the clinical study-trial of probiotics in the field of gut-liver interactions
- Responsible for design and development of clinical study-trial protocols and case report forms
- Represented clinical science in cross-functional teams and committees that have therapeutic area and organizational impact
- Supervised International Educational Project in laboratory management and diagnostic (Russia, Sweden, Norway, Ukraine)
Accomplishments:
- International Travel Grant Awards for Excellence in Research, American Association of Clinical Chemistry, 2004, 2005, 2006
- Published peer-reviewed paper (Kirpich I.A.et al., Alcohol. 42(8):675-82, 2008) for the first time demonstrated the significance of the intestinal microflora and hepatoprotective role of probiotics in the pathogenesis of alcoholic liver disease
1997- 2001, Assistant Professor
Department of Physiology, Medical School, Northern State University, Arkhangelsk, Russia
- Conducted clinical study aimed to optimize diagnostic of neurological disorders associated with vitamin B group deficiency in alcohol withdrawal syndrome
- Responsible for addressing and resolving medical/safety/eligibility questions in clinical study
- Responsible for data analyses, publications and patents writing
- Provided assistance to laboratory technicians in biochemical assays
Accomplishments:
- Published 4 peer-reviewed papers, presented 5 posters at the scientific meetings
- Two patents in the field of molecular diagnostic of the neurological diseases
EDUCATION
Doctor of Biological Sciences, 2001, Northern State University, Arkhangelsk, Russia
Ph.D. in Biology, 1997, Pomor State University, Arkhangelsk, Russia
M.S. Biology, 1991, Lugansk State University, Lugansk, Ukraine
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